Topical Stem Cell Treatment Offers Hope As Hair Replacement Therapy – IFLScience

A clinical trial published in the journal STEM CELLS Translational Medicine has detailed a novel therapy for hair loss that uses stem cells to initiate hair growth in people who have lost their hair. The treatment involves a topical solution applied to the scalp, correcting common types of hair loss such as male- (or female)-pattern baldness.

The official name for this kind of hair loss is androgenetic alopecia (AGA), which is a condition caused by genetic, hormonal, and environmental factors. Around half of all men are affected by it, as well as almost half of women above the age of 50, representing millions of individuals worldwide. It’s not a harmful condition and isn’t necessarily something that requires treatment, but for some it can negatively impact their self-esteem and in turn their psychological well-being.

There are existing treatments for AGA currently approved by the FDA, but in men these have been found to be associated with loss of libido and erectile dysfunction, demonstrating there is still some way to go in establishing a safe and effective treatment for all sexes. Recent studies have shown that adipose derived stem cells (ADSCs) secrete growth hormones that help cells to proliferate and promote hair growth. 

“However, no randomized, placebo-controlled trial in humans has explored the effects and safety of adipose-derived stem cell constituent extract (ADSC-CE) in AGA,” said Dr Sang Yeoup Lee, of the Family Medicine Clinic and Research Institute of Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital in South Korea, in a
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