Fujifilm Irvine Scientific takes on distribution of substrate that supports cell therapy research – BioPharma-Reporter.com

Cellnest was designed and manufactured by Fujifilm Corporation.

“Fujifilm sold cellnest through other company channels previously. However, Fujifilm Irvine Scientific is best placed to sell these products since they are complementary to our portfolio of cell culture media for primary cells. We joined Fujifilm in 2018 and synergies such as this are part of the Fujifilm life science strategy,”​ said Lori Serles, spokesperson, Fujifilm Irvine Scientific.

Attachment substrates mimic the extracellular matrix (ECM), a complex and dynamic environment in which cells reside in vivo​, in cell culture and allow for the adhesion, expansion, and potential differentiation of stem cells.

Enabling research, smoothing regulatory process

Unlike animal-derived components, which can introduce unpredictability in results, the chemically defined, animal component-free formula of cellnest provides consistent results to researchers and can smooth the regulatory path to commercialization, claims Fujifilm Irvine Scientific.

Serles expanded on how those aspects, highlighting that natural and undefined components present regulatory and production concerns.

“There is considerable quantitative and qualitative variability in the composition of serum and serum–derived products such as HSA. Levels of key growth factors, hormone, etc. can vary widely.

“The components in media and the culture system affect attachment, growth, differentiation, phenotype etc. Ultimately that produces variability in in the culture system. While that might not be critical in early research, for translational and clinical research reliable results are necessary.